What Is neffy?
neffy is an FDA-approved epinephrine nasal spray used for the emergency treatment of severe allergic reactions (anaphylaxis). It delivers the same life-saving medication as an EpiPen or other epinephrine auto-injectors — but as a quick spray into the nose, with no needle.
If you have severe allergies or are receiving allergy immunotherapy (allergy shots or drops), your provider may prescribe neffy so you always have fast, easy-to-use emergency treatment on hand.
When to Use It
Use neffy right away, at the first signs of a severe allergic reaction, such as:
- Hives, flushing, or widespread itching along with other symptoms
- Swelling of the lips, tongue, or throat
- Tightness in the throat, hoarseness, or trouble swallowing
- Wheezing, chest tightness, or difficulty breathing
- Dizziness, faintness, or a sudden drop in blood pressure
- Nausea, vomiting, or cramping after exposure to a known allergen (foods, insect stings, medications)
When in doubt, use it. It is far safer to give epinephrine early than to wait.
How to Use neffy
- Remove neffy from its packaging by pulling the package open and taking out the nasal spray device. Do not test or prime it — each device contains only one spray.
- Hold the device with your thumb on the bottom of the plunger and your first two fingers on either side of the nozzle.
- Insert the nozzle into one nostril until your fingers touch the nose, keeping the nozzle pointed straight up toward the forehead.
- Press the plunger up firmly until it snaps and sprays the medication into the nostril.
You can use neffy in any position — sitting, standing, or lying down — and you do not need to inhale or sniff. In fact, try to avoid sniffing during or right after the dose.
If Symptoms Continue — The Second Dose
If your symptoms do not improve or get worse, give a second dose in the SAME nostril, starting 5 minutes after the first dose, using a new neffy device. This is why you should always carry two.
After Using neffy
- Call 911 or seek emergency medical care immediately — epinephrine treats the reaction, but you still need medical evaluation, and symptoms can return
- Tell emergency responders when you used neffy and how many doses you gave
Important Tips
- Always carry two neffy devices — a severe reaction can happen anywhere, and a second dose may be needed
- Each device is single-use — do not test spray it
- Dosing is based on weight: children 33–66 lbs (15–30 kg) use neffy 1 mg; anyone 66 lbs (30 kg) and over uses neffy 2 mg
- Store at room temperature — do not freeze or leave in a hot car
- Check the expiration date regularly and refill your prescription before it expires
- Make sure family members, caregivers, and school staff know where your neffy is and how to use it
If you have questions about whether neffy is right for you, or need a prescription or refill, contact our office.
Don’t let allergies slow you down. Schedule a comprehensive ENT and allergy evaluation at Sleep and Sinus Centers of Georgia. We’re here to find your triggers and guide you toward lasting relief.